Overmethylation

What is overmethylation?

Overmethylation (also called histapenia) is a condition that occurs when too many methyl molecules are available to add to enzymes, hormones, and neurotransmitters. We receive our methylation status in utero.

Why is it a problem?

Too many methyl groups (a carbon group with three hydrogen atoms) creates excessive levels of the important neurotransmitters serotonin, dopamine, and norepinephrine, which leads to hyperexcitability in the brain. This causes high anxiety, rumination, heavy body hair, musical and artistic abilities, an inability to sit still, food and chemical sensitivities, paranoia, and sleeping problems. Overmethylators do not respond well to serotonin-enhancing substances such as Prozac, Zoloft, St. John’s Wort, and SAMe, which can make them suicidal. Bipolar disorder and schizophrenia are often seen in overmethylated individuals.

Who can be overmethylated?

Individuals with high empathy for others, food and chemical sensitivities, and an adverse reaction to antidepressant medications may be overmethylated. Verbosity is also a hallmark of this condition.

How can we fix it?

Overmethylators have a genetic tendency to be very low in folate and vitamin B6, in addition to other important nutrients. This condition can be safely corrected and balanced with dietary and nutrient therapy, as well as lifestyle modifications. First, let’s see if you might be impacted by this. Take my free, five-minute life assessment to find out if this applies to you.

The High Folate Diet Cookbook A Healing Guide for Overmethylation

Get My High Folate Cookbook

A Healing Guide for Overmethylation

Methylation is a complex process but eating according to your methylation status doesn’t have to be. My High Folate Cookbook contains high, low, and moderate folate foods, verified research, meal planning, and delicious high folate recipes to heal overmethylation (too many methyl groups).

Includes 25 recipes: breakfast, lunch, dinner, appetizers, and desserts.

Files delivered: PDF via instant download.

Overmethylation Articles

Methylation Diet Tips: Eating Right for Your Biotype
Methylation

Methylation Diet Tips: Eating Right for Your Biotype

In our world today, knowing what and how to eat can feel like a daunting task. And the plethora of dietary theories an...
Continue Reading ›
What is a Methylation Disorder?
Methylation

What is a Methylation Disorder?

Methane is the simplest organic chemical, consisting of one carbon atom and four hydrogen atoms. In biochemistry, ther...
Continue Reading ›
Folate: Friend or Foe?
Methylation

Folate: Friend or Foe?

Could folate be your friend or foe? Yesterday I was perusing my fitness magazines and couldn't help but notice all th...
Continue Reading ›
MTHFR Methylfolate vs. Folic Acid Facts and Myths
Methylation

MTHFR Methylfolate vs. Folic Acid Facts and Myths

In today's post, Dr. Albert Mensah and I address the facts and myths surrounding MTHFR methylfolate, folic acid, and f...
Continue Reading ›

Overmethylation Podcast Episodes

EP 02: How Nutrient Deficiencies And Overloads Impact The Brain And Body
Podcast

EP 02: How Nutrient Deficiencies And Overloads Impact The Brain And Body

One month in, my client Amanda told me: “I had no idea my anxiety, racing thoughts, and fatigue were due to being se...
Continue Reading ›
EP 03: How Biochemistry and Genes Impact Your Brain with Dr. Albert Mensah, MD, BCIP
Podcast

EP 03: How Biochemistry and Genes Impact Your Brain with Dr. Albert Mensah, MD, BCIP

Our stories are extremely powerful and contain genetic, epigenetic, and transgenerational narratives.  Educating you...
Continue Reading ›

“Sami’s guidance is cutting edge. She offers a unique perspective that is evidence-based and through proper testing helps to identify and uncovers any core imbalances within the body that are creating havoc. For me, deeper restoration and healing has finally come after 25 years of searching and trying a plethora of medications and dietary protocols. Before finding Sami I was uncertain if I could live another day. Sami is incredibly wise, knowledgeable, and empathetic; drawing from her large reservoir of training as well as her own personal experience. Sami’s ability to consult with Dr. Albert Mensah, a brilliant Physician in this field, is an added comfort and bonus. The healing process is not easy, but if you are willing to trust Sami’s guidance, and persevere with the dietary changes and daily nutrients, I feel confident that you can know greater health and freedom that is lasting.”

SYDNEY SYKES

Schedule a Free One-on-One Consultation

If you’re ready to start your healing journey, schedule your free one-on-one consultation to discuss your current mental and/or physical health challenges, history, and desired health goals. Take the first step on your healing journey today.

Scroll to Top
.