Ashwagandha May Have Dangerous Repercussions

Ashwagandha: Herbal Remedy with Dangerous Repercussions

This week Dr. Mensah and I discuss Ashwagandha and the hidden dangers in his adaptogenic herb that you need to be aware of.

Daily I hear my clients talk about “adrenal fatigue” and how they have to “fix” their adrenals. What I’ve discovered is that most people are confused about the true underlying cause of their adrenal fatigue or more accurately put, oxidative stress.

Ashwagandha is touted as a wonderful remedy for adrenal fatigue, but in our world, we see that adrenal fatigue is secondary to copper toxicity and systemic oxidative stress.

Many of our patients have admittedly tried various herbal remedies that they believe will enhance their recoveries. Ashwagandha, also known as winter cherry, is a powerful herb in Ayurvedic medicine. The herb grows in India, the Middle East, and northern Africa, and is in the same family as the tomato. Due to its increasing popularity in the west, it is now also being grown in North America.

Ashwagandha proponents claim this herb can be used to alleviate stress, fatigue, low energy, improve problems with learning and concentration, reduce anxiety, stabilize brain-cell degeneration, lower cholesterol, and reduce inflammation. This popular herb is being touted as a fantastic immune booster and superfood. Ashwagandha is often called “Indian ginseng” because it is very energizing, but botanically speaking, ginseng and Ashwagandha are completely unrelated.

I urge you to be careful about buying into marketing claims. Ashwagandha can do a lot of damage to folks with abnormal methylation issues and copper toxicity.

Saliva-based adrenal stress index tests are the most common testing method to determine cortisol, DHEA, sex, and other hormone levels that impact energy production. Keep in mind that if your hormones are present but are not activated, then they are not doing their job even though they are present.

Hormone production needs a feedback mechanism. Hormone levels are not an indication of hormone activity. This is why we look at the methylation cycle. If this is not in balance, methylation disorders could hinder optimal functionality of hormones and feedback mechanisms that drive hormone production, especially those produced by the adrenal glands.

Proponents of Ashwagandha don’t understand the connection between elevated copper levels, methylation cycles, and adrenal fatigue. Hormone therapy, glandulars (such as desiccated glandular supplements), and/or herbal remedies may be problematic for you and may create adverse symptoms that can impair your progress, especially if you have a methylation disorder and/or copper toxicity.

This is because most adrenal supplements contain copper carrying and stimulatory ingredients (such as organs and glands, and adaptogenic herbs) that can be detrimental to the methylation cycle.

The first question one should ask is “what’s causing my adrenal fatigue to begin with?

Excess copper, elevated kryptopyrroles, and undermethylation are classic underlying causes of chronic fatigue. Copper is especially insidious as it causes an increase in norepinephrine that puts stress on the adrenals, thus impairing hormone activity.

Our protocols for oxidative stress work at the root biochemical cause of your adrenal fatigue, making the need for potentially damaging herbal adaptogens unnecessary.

 

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Comments 154

    1. I have used ashwaghanda and it made me feel ill . The negative outweighed whatever positive that supposedly it was doing . extremely uncomfortable feeling in my throat .you won’t want to talk . It’s a sick ill feeling . It also elevated my body temperature and I felt uncomfortably hot …even inside the house in a/c . it made me feel weak and faint . I am not sure why but it made me feel ill and I was not taking any medications with it . I guess my immune system just can’t handle it

        1. I agree it made me feel very weak, difficulty in breathing, diarreha and stomach ache. Think it does not suit my digestion system

    2. Me and my daughter have found great help with Ashweghanda putting in capsules and swallowing. Helping us a lot. We no longer take the ssri snri type medication. It helps with energy.
      I’ve had chronic fatigue since a car accident this has helped me with that. I don’t know about negative effects as only found positive for me and my daughter.

    3. I agree. There’s so many people I know personally that Ashwagandha has literally changed their life. And no longer take any medications due to it. No more ambien for me as well with other meds. I do believe this is in the hands of the marketing right now. They are giving 1950mg as the number one selling product on amazon with Black pepper extract! That’s way way to much and how many bad reviews about Ashwagandha causing stomach problems? Stop taking dosages we don’t have research for and I stopped taking the brand with black pepper extract and I had no more stomach problems. Also you have to take a day off and cycle you don’t take this everyday for the rest of your life. And is this better than what your pharmacy is giving us? Of course. Will it work for everyone? Of course not. Just be careful don’t get sold by marketing know what works for you. Lower dosage could be the simple change in their negative results and products! I’m in a better mood, I haven’t had a panic attack In a week or two and I can’t remember the last time I didn’t get 2/3 everyday. So, we will take What is effective Ashwagandha isn’t going anywhere. There’s to many people who prefer natural supplements than detoxing off well, there’s to many medications to name…

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      This post is based on clinical research with patients, not research data that may or may not apply to someone with severe oxidative stress. Research states things in black and white, but in a clinical environment, there are many shades of grey. I encourage you to peruse forums such as this one where real people are sharing their disastrous experiences with ashwagandha. This post is not alarmist, it is an accurate representation of what Dr. Mensah and I see clinically.

      1. A well-researched paper on Aswhagandha.
        https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252722/

        Perhaps the real reason why so many people cannot tolerate Aswhagandha and why it could be dangerous is because a lot of people find themselves, through no fault of their own, on combinations of SSRI’s, z-drugs,benzodiazepines, anti-convulsants (mood stabilizers), other atypical anti-psychotics and or other anxiolytics. As such, their system may have a very hard time tolerating something like Ashwagandha, because many people may just be depleted and tired and feeling very sensitized simply because of being incorrectly prescribed many psychiatric drugs in sequences and/or dosages that are not recommended. I feel that this is the real reason that many people have problems with herbals such as this one. I don’t think that the problem is necessarily intrinsic to herbals such as Aswhagandha. It lies into the actual Rx lists that people actually take. The times of content people taking a single SSRI and a blood pressure medication are long gone. Many are now found on puzzling concoctions of pharmaceuticals that cannot be stopped, yet cause more harm than good in the long run.

        1. I’m on zero medications and have a hard time tolerating Ashwagabdha. I think it’s more likely that some peoples biochemistry make them more susceptible to the potential negative effects .
          I cant tolerate caffeine either. It’s rarely one size fits all in medicine ( or life in general).

        2. I don’t take any SSRI’s. I have hypothyroidism and hashimoto’s and tried ashwagandha because I was told it was good for thyroid issues. Every time I take it at night to help me sleep, it causes heart palpatations. My heart literally stopped for a second and kept doing this throughout the night. I was honestly afraid to go to sleep. It was scary so I’ve stopped taking it.

          1. Same to me. Ended up in ER with palpitations every 15 seconds to one minute. Scary. Chalking it up to this herb because everything camr back normal besides the PVC’s. Not taking it again!

          2. The same thing happened to me. I took it once and knew it was that. Never taking it again. People act like just because something is an herb or all natural means it can’t harm you, but that is false.

        3. I’m bipolar 1 and take several meds. Can I take Ashwaganda long term. Also curious about Maca and Gotu Kola long term use? I don’t find many entries about psychiatric meds and herbal use. I could expand if you comment.

      2. The first two weeks I took Aswhagandha it helped considerably with my social anxiety. Then suddenly it stopped and my general anxiety was as high as it’s ever been. Does something change with potency after a short time- is this a common reacation?

        1. I’ve found this too. It helps me considerably with anxiety for around 2 weeks before then making me feel really ill, cold (i assume from lowering my blood sugar), and more anxious than without it.

          1. Ashwaganda almost killed me last week, I was taking it for about two weeks then all of a sudden I started feeling weak and depleted my heart rate was dropping down to 37 bpm!
            immediatly I stopped taking the ashwaganda and saw the Cardiologist the next day and he said I had arrhythmia! and ordered blood work and an echo.
            so that evening I came home after seeing doc I started noticing my heart rate going back to normal.
            went the next day for my echo and blood results everything was perfect heart rate was about 90% better.
            will see doc again next week for a 24 hour monitor, just tp be on the safe side.
            im 100% sure it was the ashwaganda 🙁

          2. Do you take it for two weeks then stop and retake? Does it work when you stop/start again? Currently experiencing this same thing. The impact it has was life changing, now I feel my general anxiety has worsened as it’s stopped working and feeling discouraged.

    2. I took this back in November and had some nausea/ stomach issues. At first, I chalked it up to having the flu but as I realized there maybe was a connection, I decreased daily intake to every other day then quit completely after a couple weeks and my stomach started to feel better again. My husband takes this often and has know issues; it really helps his stress. So, lately I’ve been going through a tremendous amount of stress and decided to try one caplet yesterday evening. I should probably point out that I had a half glass of wine earlier, not a lot of calories eaten for the day, and I ate a basil leaf out of our garden. I noticed my stomach felt off about 15 minutes after taking the caplet. About an hour later, I was projectile vomiting several times to the point of vomiting bile, and dry heaves. My stomach, is just now seeming to feel normal. I don’t know if I’m allergic to something in ashwagandha or if I’m having issues with some of the areas they talk about in this article. I definitely can not take this, however it works great for my husband.

      1. I decided to take Ash to supplement hypothyroidism issue in hopes of boosting metabolism. I took it once and, within 30 minutes, I became violently ill. Severe and almost unbearable abdominal pain, vomiting bile and diarrhea for almost 24 hours. I’m grateful that I’ve never had digestive issues, so I was pretty scared and my husband wanted to take me to the hospital, but I realized it was obviously the Ash and, in light of COVID, I prefer not to go unless absolutely unavoidable. I felt human again the next day with some residual abdominal pain but tolerable. Simple premise is that if something don’t feel right, it’s not right. Things you only do once! I can’t imagine even considering developing a tolerance for it.

      2. Thank you for sharing your experience. I too started taking Ashwagandha to assist with hormone imbalance and general anxiety. I could not find anything online that suggested it can cause severe vomiting and diarrhea. I have had both symptoms, and originally thought it was COVID-19. It was recommended I take it after eating, that only ensured there was something to come up when the nausea symptoms took effect. Not for me, and I think I’m done trying to make it work for me.

      1. I bought ashwaganda last year in powder form tried it In my smoothie and was violently sick a couple of hours later, I thought I had a bug but next time I tried it same thing and the nauseous feeling was very bad. Just recently I bought a mixed green super food powder not realising it had Ash in it and once again very sick so as we know one size doesn’t fit all.

      2. How long did it take to exit your body do think? im so lost, i started taking an herbal hormone supplement (Ashwasgandha among other herbs) and my life went upside down. Im healthy, althetic, 40 year old female with no symptoms and honestly picked this up on a whim to help with energy and skin….Ive been to the ER and primary, lots of EKG’s labs etc. I just want to know when to expect it to be out of my system. I took it for 3 weeks.

          1. YES! And my primary just called, all my blood tests were normal. I have been going insane trying to understand what was happening. It started with what seemed like heart racing, and brain fog then turned into severe anxiety (which I have never experienced before) and I chopped it up to thinking I was panicking of what I could have developed i.e. Hyperthyroidism…..literally to the point I couldn’t drive over a bridge because I began to panic so bad. So scary to feel so disconnected.Now Im just trying desperately to know when will this get out of my system. And I do not take any other meds just a multivitamin.

  1. I tried the so-called adrenal remedies, including ashwaghanda and had disastrous reactions that landed me in the ER a few times. I’m convinced I have severe methylation issues and copper toxicity but can’t afford a pricey practitioner after spending thousands on false hopes. Just be cautious of anyone who pushes expensive supplements. As I know now, there is a root cause that drives adrenal fatigue. That is what needs to be identified and addressed first.
    Thank you Sami, for stating the obvious and reassuring me I’m not a crazy hypochondriac.

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      1. WOW I JUST FOUND THIS I have MTHFR too, fibromyalgia, POTS, and CFS, and I have been taking ashwagandha the last few days and I have been feeling extremely fatigued the last two days and noticed my tachycardia is worse today! I am glad I found this.

    2. I began taking an herbal supplement called Stresscare, which does include ashwagandha. I have recently stopped taking it as often and I’ve now developed an inflamed thyroid gland in my neck and realize I have the symptoms of hypothyroidism. Should I start taking it again? Or should I just try to treat the thyroid symptoms with diet and rest?. I have taken chelated chromium in the past to lower my copper levels. I can start taking that again. It has worked for me before. I think that this supplement was a bad idea because there are so many ingredients that I have no idea how or what is affecting me. After a few months I did notice stronger hair, more energy, and better focus. However I think that this may have just rebalanced my adrenal function and then I should have stopped taking it. I am just hoping I have not done any permanent damage. Here is the link to the supplement:
      http://himalayausa.com/products/best-sellers/stresscare/

      1. Interesting. I have thyroid issues ( hypo ) for years and cannot tolerate Ashwagandha
        Winder if there is a connection.

        1. I have hypothyroidism too… but everytime I take a thyroid med a breakdown follows.

          No different with ash… I had like a 7 day honeymoon period then wham. Made my ocd crazy and depression worse.

    3. I’m currently going through a breakdown that happened while taking this. Um I’ve been on a thyroid 3 times and each time its ended like this. The previous two were levothyroxine 25 (50 for like a week the first time). This one feels different though like a more spacey feeling at times, some manic, and waking up every morning with a crap ton of anxiety to the point where I gotta melt down

  2. Thank you Sami for another enlightening and thought provoking article. It seems that so many people are diagnosed with, or trying to treat their ‘adrenal fatigue’. There always seems to be some mystery as to what exactly that is. I also see that eating dessicated thyroid from a pig each day is a popular treatment for thyroid issues.

    I accept that the underlying causes could be undermethylation, elevated Pyrroles, elevated copper etc. I would also love to know what it is that may make Ashwaganda or dessicated glandular supplements problematic or “create adverse symptoms and impair your progress”.

    Could you possibly expand on this any further?

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      Hi Michelle,
      Most adrenal supplements contain organs and glands that are high in copper. Ashwagandha is a stimulant and like all stimulants, has the ability to impair detox pathways thus making oxidative stress worse, even if there is an initial increase in energy.

      Our concern, and the reason for this post, is that folks suffering from copper toxicity and/or any of the aforementioned issues are taking these supplements without a clear understanding of the true cause of their fatigue. Ashwagandha is especially detrimental if you have a thyroid imbalance and are taking thyroid medication – http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296437.

  3. Sorry, but my brain is too scattered. I don’t understand the why on not taking Ashwagandha. What is the bad that it does? I’ve always read good things about it. Can you expand more?

    Also – the above comment on thyroid. Naturethroid and the like is the only way to go on helping the thyroid if you need supplements thyroid hormones. Synthroid is a joke.

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      See my reply to Michelle. Regarding bio-identicals vs. synthetic thyroid replacement, everyone’s body responds differently to hormones regardless of the source. Some of my patients respond well to Synthroid and cannot tolerate the bio-identicals. Some do better on animal-based options. Everyone is unique.

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    2. Thyroid problem is often secondary to adrenal exhaustion. Once the adrenals are fixed they stop instructing the thyroid to produce reverse T3 and the hormones settle naturally.

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      1. Yes, I took it for a month and stopped a month ago. I am Still having issues. It has caused severe anxiety, tremors, heart palpitations, insomnia and just a manic type of feeling. Who would have thought? I don’t know when I am going to get better but it is horrible!

  4. Interesting! I was taking it during the year leading up to my crash. I had heard it was good for hormones and was taking it for cramps. I wonder how much it had to do with my issues… Thankfully, not taking it now!

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  5. Hi Sami, I have Pyroluria and an Undermethylator and last year suffered from PTSD with Adrenal Fatigue. Also menopausal! Are you suggesting that anyone with these issues should be careful with Ashwagandha? I have been taking adrenal supplement containing this for 6 months as well as being treated for Pyroluria and copper/methylation which have improved mood but I am still quite fatigued! Could this be why?

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  6. Should an undermethylator not be taking dessicated thyroid for thyroid disorders? I have Hashi’s and have always been told to ask for the dessicated instead of the synthetic. Honestly, none of the medications (synthetic or dessicated/natural) have made me feel any better.

  7. Oh my God, I’m high copper and I was taking the dessicated thyroid. I gad no idea that it could contain lots if copper! Is there any research that prooves this?

  8. My naturopath put me on Ashwagandha for my anxiety due to a lot of anxiety from PTSD. I’ve been on it for 3 months. How does it affect you badly?

  9. Thanks for this article, makes so much sense, wish I had read it years ago, always new there was a root cause I needed to uncover and I have just had testing to find that I do indeed have copper toxocity and pylori.

    Thankfully Ashwaganda is not one I have relied on but I have tried it. I do rely on other adaptogens though to help cope with my high cortisol. It dampens symptoms but I know I am not addressing the root cause with them.

    Question is how to address these underlying issues effectively, inaddition to adding b6 and zinc supps? Adding zinc creates huge anxiety for me its so distressing I am unable to supplement at the requred level.

    Thank you

  10. This article is not completely correct. As will all foods/herbs/spices/plants dosage is key. There is the therapeutic/health dosage and there is the medicinal/functional dosage. The therapeutic dosage for Ashwagandha (for everyone) is between 100mg to 250mg in divided doses per day. The functional dosage can go upto 2g. At low doses it does regulate neurotransmitters providing an anxiolytic effect.
    “Ashwagandha is used in Ayurveda to balance vata and kapha; in excess, and because of its heating, unctuous, building nature, it can imbalance pitta, and also worsen ama (toxic build-up).”

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      Author

      I encourage you to actually read this article in its entirety. It was written to inform those with abnormal methylation issues and copper toxicity that ashwagandha can do a lot of damage. This is what we see clinically. Therapeutic dosages for these individuals are still harmful. Keep in mind we are all biochemically unique. What works for one person does not work for everyone, even at lower doses.

      1. Hi Sam,
        For someone who is healthy, not taking any prescribed drugs, but has general anxiety disorder (from low to medium I.e. heart race but no panick attacks), I am seeking herbs to help minimize the underlining anxiety and provide better clarity, brain function as well. With that, do you feel ashwagandha could provide benefits? Thank you.

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    2. I recently took Ashwagandha, a new Doctor. I had been up since 3 am. i experienced a huge panic attack. I have ptsd. I think I may have taken too much. It comes in a squirt mechanism. Thank God there were friends I could call or I might have ended in the ER.

  11. I was wondering.
    Is a nutrientbalancing program through a hairmineralannalys just as god as loking at metylationstatus.
    In corekting metylation problems.

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      Author

      HTMA is a great diagnostic tool, but it’s not the holy grail many make it out to be. It is not useful in determining methylation status, nor does it replace the need to check methylation status.

  12. I belong to support group named bioavailable copper. On Facebook. I think you should look at what it says about toxic copper as opposed to bio available copper. Very interesting information. I would like to know your thoughts about this form of copper.

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      I’m well versed in the difference between copper toxicity and bioavailable copper. It’s never about eliminating all copper from the body. Zinc and copper must be in balance with one another.

  13. Ashwagandha has been used for literally thousands of years with generations of people who understands how to use it and respect the great power it holds. Any herb can be harmful in the wrong hands, ashwagandha is single handedly responsible for healing my son’s extreme eczema that doctor’s couldn’t treat for 3 years. I use it daily as do my children and when combined with triphala and chavanprash, have become the only supplements needed to keep my family balanced and healthy.

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      I’m so glad it’s been beneficial for you, Lisa. You hit the nail on the head with this statement “Any herb can be harmful in the wrong hands.” It may work for you and your family, but it is not appropriate for everyone, especially those with the chemistries mentioned in this post.

    2. It has been the only thing that helped a horrible onset of adult acne. For a year I was getting clogged pores and it was spreading. Nothing helped. Tried organic , natural, drug store, curology etc…2 weeks in 1 capsule at night (organic India) brand my skin is 80% better already. I am thrilled with it! Helps me sleep like a baby as well

    3. It caused severe heart palpatations when I’ve taken it. I felt my heart actually stop several times and I was afraid to go to sleep for fear my heart would stop in my sleep. I have hypothyroidism and hashimotos. Ashwagandha is a nightshade and should not be taken by people with autoimmune diseases.

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  14. Hi,Ive been taking ashwaganda 200mg as part of a propriety blend for thyroid support(NaturesWellness),also taking homemade pine pollen tincture for boosting testosterone, while using( Lidell)VitalAge Defiance ) used to be called Vital HGH like 10 years,ago,and it contains homeopathic ingredients,which includes pituitary,hgh,hepar suis…sources unknown..My question is: what are the (copper toxicity ) symptoms that one would get from ashwaganda if taken with glandulars/androgen boosters.. I have develeloped a rash on inner thigh that looks like either eczema, or several other ailments since using all of these supplements ,thanks

  15. Thanks for your article, which I found while websearching! I am a miserable menopausal woman, with untreated hypothyroidism (my levels aren’t THAT out of whack, so I mostly get along ok). I’ve been having horrendous hot flashes, irritability, anger, total unpleasantness! I took a morning saliva test and found that my cortisol is very low in the am (3.2), and my estrogen to progesterone levels are low, too (pg/e2: 84). I began using natural progesterone and estrogen cremes, and yesterday, started taking ashwaghanda. I must say that I probably took more than I ought to have (this is a tincture prepared in alchohol, and poured into my glass of water what I figured was one dropper’s worth). I felt many strong (and I mean STRONG) emotions and sensations. I felt anger, sorrow, almost a druggy sort of sleepiness, hopelessness, irritability, and I had wierd thoughts as I rested). Have you any idea of why this may have happened? Isn’t ashwaghanda supposed to help adrenal fatigue and get my hormones back in line? Thank you.

  16. I tried Ashwaghanda for a couple days and was totally out of it. I had zero concentration and I was totally scattered. I already feel that way from hypothyroidism and don’t need any of it. Thanks for the info, I do have methylation problems and didn’t realize the connection till I came across your article. I have not found anything to help my concentration problems which is the most frustrating part of this.

    1. I have found that my biggest concentration problems are due to Gluten intolerance. You might want to go off of Gluten for 3 weeks and see if that fixes the problem.

  17. I appreciate this article! Thank you for posting it.

    I’ve been doing lots of digging into both ashwagandha and moringa to see if either of them could potentially help my husband who has suspected food sensitivity or adrenal fatigue (difficult time digesting vegetable; is DEEPLY tired upon waking, in the afternoons, and evenings; sometimes gets these odd cyst-like, deep, red, sometimes pussy body zits, and very dry skin)

    I don’t know where to turn with my tight budget, to be honest. I was hoping some herbs could help and I have found a few seemingly thorough and reputable studies on the effectiveness of ashwagandha. But it seems everything that I find on various topics that might help (i.e. ashwagadha), there is something out there (if you research enough) to show you that it isn’t safe or truly effective and then I’m stuck back at square one.

    I’m really at a loss for what to do. Do you have any resources you recommend to determine the cause of adrenal fatigue? or would you recommend going straight into an elimination diet and skipping supplements?

    I’m sorry to ask so many questions – I realize this is a ridiculously long comment and not exactly what you are probably looking for in the comments section. I also realize that you may not be able to give advice like that in the comments section. TIA for whatever feedback you are able to provide. 🙂

  18. My husband and I both started taking Ashwagandha with L-Tyrosine about a week ago. He was on SNRIs for a year, and was suicidal. He accidentally took an MAOI and ended up in the ICU and almost died. I am extremely stressed out. We live outside the US in a place where I can buy supplements, but can’t get treatment for “methylation” and the other things you recommend. So I just tried my best to do my own research, and found out that this herb is probably what is causing our anger. We will stop taking it.
    If possible, please explain more about Methylation and Pyrrosines and how to balance your fatigue naturally. Thank you.

    1. Yes, Ashwagandha alone can cause severe anger and evoke even suicidal thoughts! I once almost committed suicide taking Ashwagandha, once very depressed, and overall I felt extremely angry, frustrated, and agitated even over simple matters or things in life. I am from India, so I was born with traditions of Ayurveda in my country, in Ayurveda and India is where this medicinal plant touted for it’s medicinal properties for the first time to my knowledge. If you still want to take Ashwagandha, then combine Ashwagandha with amla which is also known as Indian gooseberry (two scientific names for it: one: Phyllanthus emblica and another name: Emblica officinalis, so just one herbal fruit named with 2 two different scientific names as they both point to this amla herbal fruit which is from India and the fruit is green in color). Why you should take Ahwagandha with this fruit? Because, Ashwagandha is very heating in nature and this fruit amla is very cooling in nature to the body in stomach, large intestine, small intestine, kidney, pancreas, liver, heart, lungs, blood, blood vessels, and to the whole body like said. So, combining these two heating and cooling herbs can bring balance and harmony to the body as Ashwagandha’s heating potency to the body can make you anger like how it did for me. However, if it is still causing you anger, then drop and cancel Ashwagandha out of your life. Good for you

    2. However, the dose of Ashwagandha is very important, like whether you are taking a small or large dose, more important than how you take it, when you take it, with what you take it. Very importantly, whether you are taking raw Ashwagandha or its extract (Ashwagandha extract). Ashwagandha extract is very potent as its so concentrated than its natural, diluted raw form. Ashwagandha extract may only account for the 5% or 10% extract or essence from the raw Ashwagandha powder, extracted out through chemical solvents like ethanol and this extract is more potent, powerful, and concentrated compared to its raw and natural form. Like, you can imagine that 5mg of Ashwagandha extract is as powerful as 100mg of raw Ashwagandha powder, so if your doctor advice you to take 100mg of raw natural form of Ashwagandha powder and you mistook that and consumed 100mg of Ashwagandha extract, instead of its raw form. Guess what, you have taken 20x or 20 times of the recommended or prescribed dose of Ashwagandha from your doctor for example. Note, this is just an example, the standard dose of Ashwagandha extract seems, 125mg, 250mg, and 500mg respectively, this 5mg and 100mg of the extract I mentioned above is just for example, analogy, and metaphor purpose only. So, obviously you can take dose larger than that 5mg or 100mg of the extract, depending on your needs. Remember, I am not a doctor or physician, nor I have the appropriate degrees to recommend these for you. All these are from my personal experience and opinion. So, take my opinion, experience, advice under your own risks! Thanks for reading

  19. I assume if I am an overmethylator and high in copper I should not take ashwagandha?
    I see a lot about under methylation but not overmethylation and ashwagandha in the above thread.

    thank you!

  20. After taking 5HTP for two days I began to experience tingling in my feet. I stopped taking it immediately. The tingling was going away although my legs were and feet were tender. I took Ashwagandha and the leg pain went through the roof especially around the groin area. I don’t know what has happened to me. All my blood tests come out normal and urine samples are normal. So I don’t have EMS. I’m wondering if the Ashwagandha hurt me too. I know the 5HTP did.

    1. I experienced similar symptoms after taking supplement L-Tryptophan. Although my labs are all normal, I’m suspecting that I have ems. Especially because I’m still having pains (feels like inflammation) after I stopped taking the supplement.

  21. My doc diagnosed adrenal fatigue, but didn’t as such test for it…..She started me on Ashwagandha…I’m now concerned, what if my problems are caused by one of the other issues you mention?!

  22. I have fibromyalgia from adrenal insufficiency, and both are from Chronic Stress. I’m currently working with a naturalpathic Dr. Because in the past I worked with one and got my health back, but didn’t stay on the trace minerals after my health returned, so I had to start it again with a trace mineral hair analysis test and program. It’s been 4 months without results. How do you treat adrenal insufficiency from chronic stress? Can you heal mine with hormones? If so, id like to work with you. Also I recently started taking black licorice and ashwaganda for my Adrenals, but after reading this, I’m stopping both.

  23. I went to see an endocrinologist …took some test for thyroid. High estrogen with autoimmune Hashimoto…was given progesteron and ashwagandha. First two to three days went very well.. I had energy and libido. It was hard to swallow as it burned going down throat. One main concern was that my lungs felt pressure minutes to an hour after taking but very subtle. You can miss it. Nonetheless, I stopped taking because my body was experiencing may negative symptoms. I bought a thyroid support, night adrenal support and fermented mushroom supplement…and all thre have ashwagandha. So I was careful to take a different one once a day. Exactly same thing, lung irritation. So I am not trying any longer. I have developed an asma wheeze.

  24. Have been taking Ashwaganda for two weeks now for situational anxiety (car driving). First week seemed ok, slight increase in energy. Second week in and I experience sudden dips of depression. Last time I experienced depression was many years ago during very difficult personal events. Usually I am a resilient by nature. I am definitely not taking anymore of this Ashwaganda or any other ‘herbs’.

  25. I started taking ashwagandha because of all the positive effectiveness of the herb. I bought Natures Way Standardized 500mg capsules and took 2 a day for three days and began itching. The only thing new in my system or exposed to was the ashwagandha. Horrible at night. Obviously my dose was probably too much but symptoms started almost a week ago and I am still itching. Any suggestions?

  26. My resting heart rate goes up when I take Ashwagandha, any idea why? For now I have dropped it and started taking St Johns Wart, it seems to work best for my heart rate.

  27. Excellent article, definitely ahead of its time. I’m finding most in my family are suffering adrenal burnout/fatigue as a result of two underlying causes: (1) COPPER TOXICITY and (2) METHYLATION issues from MTHFR gene mutation common in approximately 80% of the world’s population.

    Combine the epedemic of copper toxicity + methylation issues with daily stress, excessive screen time, and retinal exposure to light wavelengths interfering with normal diurinal signaling, and you develop metabolic stuttering due to adrenal fatigue over time. Eventually you will burn out.

    You ask where the copper toxicity comes from and why its the silent epediemic? Look no further than organic foods. Commercial organic agriculture uses COPPER SULFATE as a common pesticide, fungicide, and insecticide. It renders the soil devoid of bacterial life. Copper Sulfate is a very effective poison. It induces heavy metal toxicity. The copper sulfate arrives to your home in produce and grains sprayed with it before harvest to impede molding. For nuts, seeds, and beans, it speeds up uniform drying (dessecation) for a more plentiful harvest. Add this high copper diet to copper rich water carried by copper pipes, and that’s good enough to get any body started on the copper toxicity trajectory. No need to mention the addition of copper no thanks to Copper IUD’s, organ meats, most adrenal supplements and herbs.

    Vegetarians/vegans are the most succeptible to rapid aquisition of copper toxicity. Heme iron, from the hemoglobin in animals, ideally mammals, is relatively effective at kicking out the copper. The iron takes its rightful place, keeping the Copper toxicity at bay. So if you are not eating heme iron, following a vegetarian diet, eating organic food replete with copper sulfate dessicated nuts and seeds, and produce exposed to copper sulfate, you are on track for copper toxicity.

    Symptoms of copper toxicity are similar to exposure to mercury. Cognitive impairment (brain fog) is one of the most comon symptoms. Copper toxicity interferes with proper adrenal function. Adrenals are the thyroid’s battery pack. So if the adrenals are shot, welcome to hypo thyroid conditions.

    Copper toxicity can be managed via careful supplementation following meticulous blood testing. You never supplement anything unless you check for the levels of that supplement in the body and the metabolic pathways of elimination. Supporting liver function via N Acetyl Carnatine + Glycene is one way to support the livers normal function of dumping copper or making the copper that arrives, the bio-available form of copper that is necessary for normal biological processes.

    Before you get too discouraged by copper toxicity dumping, remember that our bodies and natural environment were never designed to have such an overload of unboud inorganic copper exposure. You nearly have to trick the biological system to loosen the unbound copper. Initial detox is HELL.

    1. How do you trick the body? To loosen the copper? It was suggested to me to support the adrenals to deal with copper overload naturally. I do horrible with holy basil and awashaganda it seems. And I am overmethylated so I don’t see how I could tolerated bovine adrenal cortex.

  28. As with all imbalances in the body it’s the interactions between the various bodily systems that is at the root of health or health problems which obviously suggests that one supplement is not a Permanent answer, such that any one supplement could Backfire. To reduce problems is to have a better nature diet ( if you can). and add ( carefully) a blend of minerals/ vitamins which are known to be in short supply – even in organic foods .Today’s toxic planet/ soils/ water is top of the list for health problems. One thing that may help is a regular fast. Give the functions of the body time to catch up— obviously meditation, Fresh air, filtered water Remember there’s an interaction between the mental/ emotional and physical. No- one is going to be perfect. Please don’t overanalyze things it can get more stressful. It is – as you already know – a balance. I have and am going through it- after exposure to toxic chemicals- it’s not easy and too expensive for lots of tests which usually prove nothing.Consider the numerous medicinal drugs dished out- the lesser of two evils AT BEST. Consider cultures in the world who live simple lives with their own simple crops. Are they as unwell as most of us? Another thing is our digestion/ absorption.My belief is our microvolts is constantly being affected by our own intelligent rulers/ manufacturers/ drug companies/ chemical producers .What is in our food. These modern illnesses were not here hundreds of years ago. Go back to basics; it is a vicious circle. If there is a problem it doesn’t necessarily mean you stimulate that gland or sedate that gland it’s the whole endocrine system – I believe. So do not overdo it with one or a couple of supplements. My opinion is to find something that acts holistically in the body. One important suggestion– listen to your intuition. Bloody hell I’m going on and on. I’ll have to take my own advice.

  29. I am new in this taken only one tablet therefore could not sleep after taking aswagandha whereas google is saying batter take in night i followed in night i.e 390 mg , now i am thinking should i stop taking it because i come to know lots of things through your article …………..i took it because there are lots of advantages goin on but surprisingly lots of disadvantages also as come to know now ……………So Sir/Mam pls suggest me guide me honestly should i take it or not counting on you & why i could’t sleep reason behind??

    Thankyou
    Saiman Debbarma, India

  30. I took Ashwaganda for about a month and in that month I became manic, resulting in a uti and now a diagnosis of chronic prostatitis. It gave me a huge boost in energy, but it also caused massive systemic inflammation. Now I’m taking cbd oil and trying to exercise regularly instead to maintain some balance along with the antibiotics. The medicine is perhaps miraculous for those with a more balanced, healthy endocrine system than I. For those who are prone to allergies, anxiety, depression, health issues caused by stress, this herb will probably do you more harm than good as it ramps up your immune system.

  31. Hi Sami,

    I’m very grateful for this article as I too took ashwagadha with disastrous results and reading this article proved me this was the herb was the cause.
    I have had CFS and still not completely back to normal but I’m far more functional now. Ive had my genes tested and I have an issue with methylation. I’ve taken ashwagadha on and off the past year or so and I suspected at one point that it gives me anxiety. about month ago I started to take it regurlarly and after couple weeks I was in A very bad state. I had palpitations, i couldn’t breathe well, I begun to get so anxious I did not sleep and I sweat so much I was soaked, I thought I was losing my mind, it was hell and I couldn’t figure out why I’m going through this now. My memory had gone, concentration and everything else that goes with anxiety too. Luckily I realised to stop taking it and about 2-3 days later I went back to normal, sleeping normal, breathing better, calm and no anxiety. I’m so grateful for this article as now I can put this episode behind me and not question my sanity anymore. Please people be aware! And I guess this is a good indicator for those who can’t tolerate ashwagadha that they may have a methylation issue which itself is tricky but it’ll change your life once you know how to deal with it. I’m frustrated with some of the negative comments here- why can’t people accept that one thing can’t work for everyone and in fact can be even harmful. We’re not all the same and this kind of thinking can be so damaging to some people.
    Thank you for this article!

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  32. Hello,

    I have recently noticed that I am producing excess saliva in my mouth and this is worse when talking to people in a meeting for example as I notice it more and it makes it difficult to speak.

    I have been taking ashwagadha as I thought it would help elevate my mood but now I am worried it is not the menopause as I thought initially but this supplement that is causing this unsettling symptom.

    Could you advise please? I should also say my last blood test said I was on the borderline for thyroid activity

  33. People seem to have this delusion that herbs can somehow bring about all these wonderful benefits with no side effects. If they are strong enough to bring about significant physiological changes, then almost by definition they can also cause adverse effects. It’s magical thinking to believe otherwise, fueled by marketing. I doubt any of this stuff would pass a really rigorous clinical trial.

  34. Be careful with this herb and watch for side effects. I do not take any medications that would interact with this. I read that this helped for osteoarthritis which I have developed. After about 3 days I started itching severely especially at night. The itching got so bad to the point I had bleeding sores all over my body including my scalp. Even my sclera was itching. I have never experienced anything like this. It took a good week to 10 days to get it out of my system and the itching subsided.

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  35. Kat, do you mind sharing your side effects? I just started Ashwagandha Supreme on Saturday (It’s Monday as I write this). Saturday was one of the best days I’ve had in months as it relates to Adrenal Insufficiency/Fatigue; however, Sunday and today have been filled with non-stop heart fluttering/palpitations (it’s like my heart keeps beating up and won’t complete the beat. It levels off at some point and then it just keeps happening.

  36. I hope you will reach out to me Sami. I’m struggling a lot with mostly anxiety and fear. For some reason I can’t seem to calm myself. I am under a Doctors care but it hasn’t done much help yet. I was searching the web for natural supplements that might be able to help. I’m trying to get my life back. Anyways I found Ashwaghanda which sounded very promises. So I look into what I could find on it. Also I came across a couple doctors on the web that reccomend this supplement. So I thought it could help me. I received it in the mail and tried it only for 2 days. Its an extract with the dropper in bottle. Said to use 28-56 drops 3 times a day with a little water. 1-2 ml dose. I tried it for 2 days at night for sleep. The first day wasn’t to bad but I became very panicky and sweaty after the 2nd day. Does it work that quickly. Also started sweating a lot. I’m on hormone replacement therapy and also hypo thyroid. Can you offer me your help? Please. I also was considering trying this supplement called Mulungu I believe from Brazil. Do you have any helpful information on that. Hope you trully can help. Thanks so much for your time. Hope to hear from you soon Sami.
    God Bless you for helping others💐🙏👼🌺 Hope to hear from you soon.

  37. I’m late chiming in here, but I also had a very bad reaction to ashwagandha (and I take no pharmaceuticals, not even aspirin or tylenol, haven’t for many years). It’s been a couple of years since I tried it (I was researching because last week I started taking a mushroom blend and I think I’m having a very similar reaction to that as I did to the ashwagandha). I only took ashwagandha for a few days, and on the third day or so was suddenly in a very deep dark place, extreme depression, anger, fatigue. I know I have methylation issues (family members have been diagnosed – I have not, but I’ve had so many symptoms all of my life that it’s a no-brainer). I immediately got off the ashwagandha and won’t touch the stuff ever again. I had a similar reaction when I started taking methylfolate. I do great with methylcobalamin. I tried dropping way down on the methylfolate dose to see if I could tolerate it if I gradually worked up to a “normal” dose, but no can do. No point in taking a supplement that makes you feel suicidal, duhhhh!! I even tried again about a year later, and had a bad reaction even faster than when I tried it the previous year, within just a day or so instead of it taking a week this time (depression, anger, fatigue), so not doing that supplement again. I’ve had great results from lots of vitamin supplements (megadoses of C and B3 in the form of nicotinic acid, pretty high dose of methylcobalamin, and “normal” doses of D3, ubiquinol, nutritional yeast), but that one I will not take a chance on again. And I know that it’s common for people with methylation issues to have trouble with methylfolate.

    The reason I was researching and ended up here is because last week I started taking a mushroom blend (reishi, lions mane, maitake, chaga, cordyceps, and turkeytail). I thought I was doing fine on it, but after several days, I was severely fatigued, depressed, extreme anger (I have things to be depressed and angry about but most of the time I’ve been dealing with it fine since I am making progress toward making some changes in my life, and had been feeling quite hopeful and happy the last 6 months). I had been really working nonstop, every day, basically every waking hour since December, and especially the previous week or two, so I thought maybe it was just that causing the fatigue and maybe even the depression. But even after taking three days off and sleeping as much as I felt like I needed to sleep, I still have this extreme anger, depression, and hopelessness, and it suddenly dinged in my head that it could be the mushroom blend, since this is so similar to how the ashwaganda made me feel. But of course all I can find online is how wonderful all these mushrooms are and what great results people are having with these mushrooms. Needless to say, I will not be taking the mushroom powder anymore, and will try to find more info on whether or not these mushroom supplements can also cause these types of side effects for some people. Dang it – I was doing fine, actually better than fine, until a few days after I started this mushroom powder! Sami, I’m going to search your website and see if you’ve possibly addressed mushrooms as well? Thank you for this article. Yet another reminder to me to be more careful because just one substance can so quickly take me from happy, energetic, and hopeful to extreme fatigue, depression, and anger, and if I’m feeling good and doing well, why am I monkeying around with it and trying some new thing that I probably don’t need, just because I keep reading how wonderful it is? I’ve fought too hard over the last 6 years to get myself feeling good again after many, many years of constant morning fatigue, not being able to wake up and get out of bed, and fighting depression. Thanks again!

  38. I started taking ashwagandha and I am now having horrible anxiety, nausea, lighthedness, and an emotional. I thought I was going through perimenopause. I am freaking out. Now that I found this I believe it might be the ashwagandha 🙁 I am super sensitive to all medications and herbs. I was really hoping it would help, but it seems to be driving me into an anxious depression.

  39. I did hair analysis test and it showed toxicity of hidden copper. I bought ashwagandha supplement to relief my anxiety, depression, insomnia and high cortisol and adrenal fatigue but after two days of taking it, it made my symptoms worse!!! I experienced the worst feeling in my life!!! I stopped taking it.

    1. How long did it take for th he feelings to subside? Cause I felt “good” for just under a week then it was hit and miss until this last Sunday when I woke up in a dark place mentally… here we are on Friday and it’s still messing around.

      1. I took it for a month and stopped a month ago. I am still feeling the extremely negative effects. Major anxiety, heart palpitations, tremors, insomnia and manic type of feeling. I don’t know when this will go away!!!

  40. I started seeing a highly trained herbalist/integrative doctor a few months ago, and she put me on Ashwaghanda tincture about two weeks ago. I have the MHTFR genetic mutation as well as fibromyalgia. After a week of being on the Ashwaghanda I had the absolute worst fibromyalgia flare I’ve had in my entire life. Extreme spasm on the entire left side of neck, trap, and clavicle. The slightest movement caused excruciating pain. It’s been a week and I’m still recovering. The last 3 days I was so exhausted I literally couldn’t do anything but nap and lay on the couch binging Netflix. Wasn’t until I just started doing my own research that I found out people with autoimmune diseases (which is one of the theories for what fibromyalgia is) should NOT EVER take Ashwaghanda, and now I just found this about how it can be dangerous for people with methylation genetic mutations. I feel like someone trained at my doctor’s level should have known this. Today was day one not taking the Ashwaghanda and the difference compared to how I’ve been feeling this whole past week is like night and day.

  41. Sammi: Great article and feed. I read all the comments and find it interesting those who love the supplement and therefore so defending of it, completely missing the point you are making. Unlike most folks who have chimed in here, I’m pretty healthy and really have no issues. As an athlete, it’s been suggested to me that I should take Ashwagandha and Rhodiola to help my body deal with stress overload. I tried both last night and ended up having an evening of diarrhea and vomiting. I haven’t heard anyone else mention this reaction, so I don’t know for sure if the supplement(s) were the cause. But I did experience a similar reaction when I tried LifeVantage Protandim which also contains Ashwagandha. I’m curious what you think about the advantages/disadvantages of Rhodiola. At this point, since I really don’t have any health issues like adrenal fatigue, there probably is no reason for me to be subjecting my body to experimental herbs.

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      Thank you, Michelle, for sharing with our community. I’ve worked with clients that have experienced diarrhea and vomited after taking Ashwagandha, too. I wish more people understood the power of herbs and that they are not for everyone. I will add an article about Rhodiola to my list. 😉

    2. I’ve tried ashwagandha root extract twice – capsule & powder form and had pretty bad diarrhea both times. I’m also very athletic and have no other allergies or health issues. Just wanted to use it to see if it can improve my mental & cognitive function.

  42. I was wondering if you can comment about a persons genetic makeup and ashwaganda. My child has the comt++ gene polymorphism. I’ve read that Rhodiola isn’t good as it uses up comt. All I know is ashwaganda made my child extremely emotional and aggressive.

  43. I started taking ashwaganda to help me concentrate. I had just started a new position at my work and was having trouble being nervous and concentrating. I had read alot of good reviews about ashwaganda and thought why not….So I took it for a few months and I felt like a million bucks…I was calm, relaxed, sleeping good and was able to stay focused alot better than what I was. Then one day it was like a light switch flipped and I felt awful…I all of sudden couldnt sleep, I felt like I had drank 5 cups of coffee and so jittery and then I started having panic attacks for no reason. I felt like I had a lump in my throat. It felt like my throat muscles were very tight especially at the back of my neck. It felt like I had a weight in my chest and it was difficult for me to take deep breaths. I was absolutely miserable.At first I thought maybe I have a lung disease or emphysema but then I just knew the ashwaganda had caused something in my body to change. I stopped taking it and my symptoms were even worse. I went to my doctor, I told them I had been taking Ashwaganda and I felt like it did something to me……Im the type of person that I dont normally take any medicines or supplements unless I really have to, and I dont go to the doctor unless Im extremely sick….. Anywho my doctor said she had never heard of ashwaganda and told me I was just having anxiety and prescribed me zoloft. I was so tempted to take the medicine just to give me some relief but I read all the side effects and I thought, no I am not putting anymore substances in my body. With Gods help I am going to get through this…. Every few days after stopping the medicine I continued to have panic attacks out of the blue and extreme anxiety for no reason. But every week that it was out of my system I felt better and better and now I am feeling 100percent back to my norm. I certainly learned my lesson about playing around with herbal supplements. All I can say is never again and thank you Jesus for getting me through it.

    1. Are you better now? I feel like been short of breath for about a month and havent been able to take deep breaths. How log did it take for you to recover?

      1. I stopped taking it a month ago and still having a lot of issues. I don’t know when I am going to get better! How are you now?

    2. Hi Rachel
      Can you recall how long it took you too feel “normal” again?
      I’m desperate. I’ve been to the ER, my Dr, and now today the paramedics came to my house. All my vitals come back normal, but I’m undoubtedly struggling with effects from Ashwaghanda in a blend with other adaptogens and sadly no one is experienced enough in that field to help. I’m relying on anything I can research because I feel helpless, I wish so bad to have my life back and that I NEVER touched this stuff.

  44. Ashwagandha by Organic India has helped calm my sister’s anxiety tremendously. She has been taking it regularly with noticeable improvements not only with anxiety but also with calming her Essential Tremors. It has proven to be powerful at calming anxiety and tension not only for her but for other family members that have tried it as well, without any side affects whatsoever.

  45. I was using the following Aswaganda supplements for last 2 years,

    Ajaswagandhadi lehyam – 1 tea spoon – 2 times daily
    Aswagandharishtam (15ml ) + dasamoolarishtam(15ml) + 30ml water – 2 times daily
    Rejuveda Tablet – 2 times daily

    My recent blood test results ,

    T3 (CLIA) 357
    T4 (CLIA) 26.7
    TSH (CLIA) 1500

    Following are my problems,
    Low body weight
    High appetite
    Weak body
    Rapid heat beat
    chest pain
    Hand tremor etc

    Aswagandha can cause all these problems? I stopped having these medicines recently.

  46. I was using the following Aswaganda supplements for last 2 years,

    Ajaswagandhadi lehyam – 1 tea spoon – 2 times daily
    Aswagandharishtam (15ml ) + dasamoolarishtam(15ml) + 30ml water – 2 times daily
    Rejuveda Tablet – 2 times daily

    My recent blood test results ,

    T3 (CLIA) 357
    T4 (CLIA) 26.7
    TSH (CLIA) 1500

    Following are my problems,
    Low body weight
    High appetite
    Weak body
    Rapid heat beat
    chest pain
    Hand tremor etc

    Aswagandha can cause all these problems? I stopped having these medicines recently.

  47. T3 (CLIA) 357
    T4 (CLIA) 26.7
    TSH (CLIA) is less than 0.01 and testosterone above 1500

    In the previous comment, I used greater than/less than symbols and something went wrong.

  48. This herb saved my life. When added to my antidepressant, I no longer feel like the cloud is hanging over my head. I no longer feel like there’s no hope. I no longer feel like I can’t get out of bed. It literally saved my life and yes we are all different, but I’ve lived with depression for half of my life and nothing has helped me like this. I haven’t had any side effects at all. I take it in the morning with my antidepressant and B12 and vitamin E. When I first got it I was taking it at night and I had trouble sleeping. Once I started taking it in the morning I noticed a difference rather quickly. It’s hard to explain how it makes me feel because it’s not like I feel energy or manic. I simply feel like a whole person again. I enjoy things now and I can laugh and even plan. I actually took it because I was diagnosed with adrenal fatigue and I am sick and tired of being stuffed with prescription medicine so I sought another way. The fact that it accidentally helped my chronic depression is just a happy miracle. I do have low thyroid as well so this article scares me a little bit, but to be really honest I would much rather live with whatever side effects it has for thyroid then to go back into the hell of my depression.

  49. This has been an eye opener. I had been experiencing Adrenaline fatigue, early morning fight/ flight attacks, anxiety. It happened 3 years ago and started again few months ago. Recently tried Ashwagandha but after 2 weeks I realized it increases my morning nervousness. Stopped it. Now, reading the article and comments I can see why. The some goes for the adrenavive supplement which I started 4 days ago during which I had 2 morning episodes of nausea and nervousness. Obviously will stop this supplement.
    So given my reaction and reading your article I suspect copper and methylation (the possibility was already raised by my Dr, but then I shouldn’t have been recommended these supplements).
    I am waiting for blood test results. But it really makes sense. Next step is finding how to deal with these issues.

  50. I took very little Ashwagandha( one single pepper size quantity) and I regretted after 2 hours. My heart started pounding and I knew that it was due to this Ashwagandha. I think it lowered my blood pressure way too low, and the heart tried to push it up hard and so I had that palpitations. It was gone after 4 days. So, please be cautious when taking Ashwagandha. It is dangerous if you know nothing about it.

    1. It has been 24 hour since I made the mistake of taking it and I am still feeling so weak and fatigued. I thought it will help me with anxiety, but I was wrong. How are you feeling now sudhakar? I am scared it will never leave my body. I was feeling so much better with just my Magnesium supplement.

  51. I’ve gone through menopause. I am on Keppra. I have a terrible memory. I can’t take a multi vitamin. My system does not digest it well, causes pain. I think it is because of the added calcium. I have had multiple kidney stones. I have to take individual vitamin supplements, excluding calcium. My gallbladder has been removed and I just had hernia surgery. My hair is thinning and my scalp is dry and sometimes itchy. I am sensitive to the sun and have extreme insomnia now.My nails do not grow and have horizontal ridges in them. What should I do?

  52. I have many chronic ongoing health problems, some questionably iatrogenic, many which are relevant to this discussion. Initially I was trying to figure out if Ashwagandha Sensoril can cause diarrhea. After reading your article and further discussion, can you please tell me the best way to test for copper toxicity? Among all kinds of other things, I took 2 different desiccated adrenal supplements as directed by my doctor for many years and take armour throid. I would also like to know if a similar reliable test can be done to check for toxicity of other heavy metals so I can request this from my PCP or find a reliable testing facility if what you recommend is not covered by most insurances. Thanks

  53. This is a really informative article. I have histimine issues so I knew taking this herb might cause problems because it’s a nightshade but my reactions are always nervous system related; pulse, bp etc. But this herb caused me major dirreah within an hour of taking on every occasion i tried it. It also made me tired yet disturbed my sleep. It should be used with great caution as all but the most benign herbs should be. Ive read it doesn’t clear the body for 72 hours so a bad reaction could last 3 days…
    Thank you for the most interesting article! Most of what you see on line say herbs have virtually no side effects becouse they are trying to SELL them. Its refreshing to read knowledge and experience based articles.

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  54. I started taking ashwagandha ksm66 a few weeks ago and got severe cystic acne, Fungal acne and a face rash, that is still here, heart palipitations, anxiety upon waking and insomnia. I did tons of research saying it’s so good for depression and anxiety, and a bunch of other benefits. I have been fine taking Nootropics and L-Theanine for anxiety, but I believe this herb is messing me up. I thought it was cuz of the zeolite, charcoal, broccoli sprout, wild yucca root, humic and fulvic acid blend I was taking or maybe the alpha GPC… I stopped the detox blend and alpha gpc 5 days ago and am stopping the ashwagandha tomorrow…

  55. I’m a 43 year old male, I eat relatively well and exercise regularly. I take no medications, and have atypical plaque psoriasis. I began taking Ashwagandha 4 days ago after hearing about its testosterone boosting ability. I naively went straight to taking the max dosage recommended on the bottle (450mg 3x daily). The first day I noticed nothing except some acid reflux however, when I woke on the second day I was extremely itchy. Both of these symptoms continue to increase in intensity. Going into the 4th day now the itching is almost intolerable and now I’m noticing more frequent urination and a mild burning when urinating. I do feel more relaxed overall. I hope lowering my dose will alleviate these negative side effects.

  56. I tried Ashwagandha for my social anxiety and fatigue. I started having MS symptoms , stopped and my neurologist recommended Lexapro, first 2-3 weeks were rough but I wish I would of been on Lexapro 25 years ago….. I’m 40. It has made such a big difference in my life. I suffered so long b/c I thought meds were bad…. I tried herbs , change of diet and self coping books on anxiety Which didn’t really help in the end. Please don’t be afraid to try a medication like Lexapro. For anyone wondering, I take it around 8-9:30 pm at night. 10mg. I do not recommend Ashwagandha, night shades are not good for your health. Do your research. This is a well written article, thank you.

    1. I took Lexipro for years and it ruined my life.

      I stopped the drug 2 years ago and I still have persistent symptoms.

      I won’t go through the list but I now have cognition issues and my vision is blurry.

      I was also “fine” on it for years so the whole everybody is different argument is a load of bs. These drugs are like Russian roulette and one day your luck might run out. Also getting of an SSRI can be really hard and sometimes people can’t do it. Those that do can end up with persistent side effects that last for years or indefinitely.

      Also any perceived effect of an SSRI is usually a combo of the placebo effect and the numbing effect inhibiting serotonin has, this is often perceived as working, or correcting the problem but it’s not true.

      People need to research head meds before taking them, most doctors are noting more than prescribers so of course their science sounds right.

      If anyone wants to read the truth about such meds, look up the Risxk site run by Dr David Healy

      Again I was fine on an SSRI for years but I had no idea what it was doing to me all along. I would gladly just have my anxiety back than the issues I have now. Remember, these issues did not start until years later.

  57. I’m 48 and started taking 400mg of Ashwagandha in September 2019 to help me focus in the gym. I felt great for the first two months. I’m an extrovert – life of the party, so to speak. But by Christmas, I didn’t care about anything at all. So I upped my dosage to 800mg from 400mg. I see now how ignorant that was. By January, I started having suicidal thoughts on a daily basis. Horrible, horrible thoughts. No motivation, no pleasure in anything, just completed discouraged about everything. Hated everyone, including myself. All I wanted to do was go to sleep and not wake up and actually prayed to God for it. That is not who I am.

    I finally started researching side effects and realized that it most likely was what has been causing these issues, as that has been the only thing I take other than a daily multivitamin. I have been off it now for a few days and realize that this is going to take time to get out of my system so my brain can rewire what was disconnected. I am in a horrible place, but realize that it’s going to take time. Ashwagandha may work for many, but it’s definitely not a wide painted brush. Be cautious or you could end up in a place like me….and it’s not a good place to be.

  58. Ashwagandha has helped me. I felt as if it controlled my anxiety and calmed me. I was also on Cymbalta 20mg while taking the Gaia brand Ash. One time I could not find any Gaia and didn’t want to go to another store to find it and tried a different brand. It made me sick. I don’t know why?? Maybe it was more potent? I pretty much never took a break from it though as it is suggested. I recently ran out and am now taking a break. I am feeling fine. I don’t know if I will go back on it. I am now tapered off the Cymbalta. It took 2.5 years to get off the lowest dose. These drugs are really, really awful!!! Best of luck to you all. If you have had a bad experience with Ash and still want to try it, I do recommend the Gaia brand. It never gave me a problem as far as I can tell!

  59. Can ashwaganda tea cause the side effects? I am experiencing crazy heart palpitations that I kept checking my wrist pulse, breathing feels interrupted whenever heart goes out of rhythm. I googled this tea and heart palps and found this thread. This tea is advertised as a stress reliever, doesn’t come with a warning. Definitely not drinking this tea again but am wondering if a weak form like ash tea could cause this unpleasant and scary side effects.

  60. Never ever take Ashwagandha in your life, it gave me complete loss of sleep and I am still suffering from it for last 2 years with no sleep at all. Even benzodiazepines are not working for me to get sleep. I am awake like 24 hrs for 2 years. I fucked up my life. I cry everyday that why I took this herb.

    1. I stopped a month ago and I know what you mean! Can’t get any sleep , highly anxious, palpitations, and when I do I sleep, I wake with severe anxiety and doom!!! I hope it it does not take 2+ years to get better! I am sorry you are still going through this! This supplement is awful!

  61. Thank you for this. I tried Ashwagandha after numerous clients and colleagues swore by it and was referred to a brand on Instagram. Promises of help with stress and anxiety, thyroid help, and balance were all things I wanted. Instead even with a teeny tiny dose I experienced anxiety attacks lasting for hours, sweating, heart palpitations, nervousness, diarrhea, sleeplessness. I felt like I was hallucinating or on some kind of drug. It was horrifying. I reached out to the company and they were no help. The hadn’t heard of such a reaction and “weren’t herbalists” so couldn’t give me any advice. Not herbalists but selling herbs online, huh?! Anyhow I was searching for other people’s adverse reactions and came up empty handed. I have no idea why I had such a hard time with it, but happy to know I’m not alone. Goes to show what works for some does not work for all❤️

  62. Ashwagandha made me feel the most anxious I’ve ever felt in my life. I thought I had lost my mind. Suicidal thoughts, horrible thoughts constantly. I took it for 3 days didn’t really feel a difference. The 4th day I took it thoughts would creep into my mind, irritation, abnormal pessimistic thoughts. The 5th day my chest felt tight, my breathing was fast, I had thoughts of killing myself. I had several panic attacks in one day which is something I’ve never experienced. I felt like I was drugged and it made me feel very fatigued yet I could not sleep. It was like my mind was harassing me with constantly fast negative dialogue. I couldn’t get a full breath in for days, just quick breathing, like I was sprinting. I just got past my period 2 weeks prior to taking this and I started bleeding again, spotting, which is something I’ve never experienced. After 11 days of feeling this way I finally researched side effects of Ashwagandha and read reviews of other people feeling this way I finally stopped. I took me 2 weeks to feel okay again. I was really concerned for myself. It’s been 2 months since this happened to me and I think about it everyday. Just thinking about what happened to me makes tears swell in my eyes. I just want it to be a distant memory. It makes me feel so much better to see people that have a similar experience to me. Please don’t take this.

  63. I started taking two supplements that contained ash at the advice of my doctor who uses Ayurvedic herbs. These were to help with my anxiety. Have taken them for about 2 weeks and the lightbulb just went on today that they have been the cause of my terrible mood and irritation and sadness. I’m pretty sure I am an undermethylator and have high copper toxicity. So this is not the herb for me. I hope I won’t have side effects stopping these supplements.

  64. I started taking this supplement in Sept 2. 2020 for anxiety. Around three week later I started having severe panic/anxiety attacks that I had never experienced before. My heart rate was extremely high and I thought I was going to die. I started having paranoia thought’s to the point that I thought I was going crazy and knew I was having a mental break down. I scared myself and my family because we did not know what was going on with me. I prayed and prayed cause I thought I was going to die or lose my mind. And a voice told me. ” it’s the pill your taking” ( I know it was God). Then I googled and found this site and started reading other people with almost or the same side effects. Herbs are very dangerous because they do not have to be approved by the FDA. I suggest you be very careful taking this supplement

    1. Hello, I had a similar experience. My doc said things will settle down a few days after stopping the supplement. Did your heart go back to normal? Thanks for the post.

  65. These are some great ashwagandha dangerous repercussions that you have discussed here. I really loved it and thank you very much for sharing this with us. You have a great visualization and you have really presented this content in a really good manner.

  66. It caused me a very, very strange side effects!! 🙁 🙁
    In my sexual life, And my period. After when i take this pills, i noticed my orgasm stops in a second. It begins and ends a second later, as if something was blocking it . Very scared me! The other side effect: I shortened my 28-day period to 21 days. Has anyone else experienced this?? If yes, please answer me. I takes a Tyroid Support vitamin and contains Ashwaganda. I’m not sure these causing my new problem. I’m copying what is contains:
    Vitamin B-12 (as methylcobalamin), Iodine, Zinc, Selenium, Copper, Manganese, Molybdenum, L-Tyrosine, Schizandra, Coleus Forskohlii, Kelp, Ashwagandha Root, Bladderwrack, Cayenne Pepper,

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