EP 53: How to Optimize Hormone Therapy with Jim Paoletti

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Many people are confused about how to balance hormones and are overwhelmed by all the misinformation about bioidentical hormone therapy for both men and women.

It’s easy to be confused because the symptoms of an excess hormone can also mimic symptoms of deficiency. Plus many people are unaware of the role diet and your gut microbiome play in regulating hormones and how nutrient deficiencies and overloads can upset this delicate balance.

But understanding these relationships doesn’t have to be so complicated. That’s why I’m honored to have pharmacist and bioidentical hormone expert Jim Paoletti on the show.

Jim Paoletti, B.S. Pharmacy, FAARFM, FIACP is an independent clinical consultant on hormones, nutrition, and wellness. Jim has 40 years of experience with bio-identical hormone therapies in clinical practice, both in retail pharmacy and as a consultant and educator. Jim served previously as Director of Provider Education for ZRT Laboratory, Beaverton, Oregon, and as consultant and Education Director for Professional Compounding Centers of America of Houston, TX.

He is a graduate and former faculty member of the Fellowship of Anti-Aging and Functional Medicine. Jim has lectured extensively and internationally on all aspects of compounding and BHRT to medical practitioners and consumers, and has several articles published on BHRT and compounding pharmacy issues. Jim has published the book A Practitioner’s Guide to Physiologic Bioidentical Hormone Balance.

Listen to the full episode to hear:

  • Why symptoms alone aren’t enough to assess hormone imbalances and treatment 
  • Why gut and microbiome health are the first step to hormone health
  • What we get wrong about men’s hormonal balances
  • How long-term use of synthetic estrogen impacts the body and why it’s not always a simple switch to bioidenticals
  • What types of testing your provider should be using to accurately assess hormone levels

Learn more about Jim Paoletti, BS Pharmacy, FAARFM, FIACP:



1 thought on “EP 53: How to Optimize Hormone Therapy with Jim Paoletti”

  1. I have a clarifying question. I was prompted to get off of hormone replacement drugs (progesterone, bi-est transdermal cream and DHEA) because of my excess copper issue. I was informed that bio-identical is no different than synthetic and thus foreign to the body. My question after listening to the podcast with Jim Paoletti is should I actually be considering taking a hormone because I’ve developed osteopenia, and I’m concerned about breast cancer since my sister recently had a double mastectomy. This episode was very enlightening and frighting at the same time because of the body changes as we age and a desire to ward off Alzheimer’s as well. Love your podcast!

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